Cardarine Review – Shocking Effects Of GW501516

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Cardarine is not a SARM (Selective Androgen Receptor Modulator) rather it is a PPAR-delta activator and brings the same health benefits to the user typically associated with SARMS. Cardarine is best to strengthen endurance and is a chemical to be stacked with other compounds to get the desired results. In the last decade of 19th century, Cardarine is formulated by Ligand Pharmaceuticals. GlaxoSmithKline also played equally in the formulation of Cardarine which is referred as Endurobol GW-501516.

The man is no more living in chaos and disorder. The caveman, who was called a brute, has now conquered time and space. Fatal diseases are not a problem anymore. Certainly we owe a great debt of gratitude to all those scientists, navigators and researchers who baffled the world with their scintillating knowledge. So, the process is still ongoing never to stop. This is how GlaxoSmithKline focused on the treatment of blood   vessels, heart and diabetes, thus developed GW501516.

To me the human progress’s downfall starts with no research situations any longer.  Why to live in dark by not conducting research? Why not reaping richer benefits by going in the pursuit of truth? The process of studies on GW501516 was stopped because of its drastic effects on animals which developed cancer in them. Still a lot of studies are to be conducted to know whether the compound has the same adverse effects on humans as well, so a thorough test based studies need to be conducted.

What is Cardarine (GW501516)?

What is Cardarine (GW501516)?

The well known compound GW501516 is referred to as Caradrine. The compound was originated in early 1990s. Its formation was purpose-based. It got popular among bodybuilders who found it to be the best SARM for fulfilling all the demands of the users. Cardarine’s uses are innumerable from boosting metabolism to treat certain kinds of deadly cancers like that of breast, colon and prostate tissues. It does not let the tumors be formed. The feature that brought distinction to the product is it is highly safe to use as compared to SARMS.

How Does Cardarine Work?

Including fatty acid metabolism, Cardarine that is also known as PPAR (Proxisome Proliferator-Activator Receptor-delta) agonist is performing a task of carrying out very important workings of the body. Cardarine, being a nuclear hormone receptor performs its function of converting fatty acids into energy in a very unique way. The novelty of its working is that it does not the glucose be stored in form of fats to be used later. This is how it boosts up metabolism in a tremendous way. In fact the human body is more inclined to change the glucose received from amino acids into fatty acids than changing that into proteins. The reason behind its matchless popularity among athletes and bodybuilders is that Cardarine in a mechanical way changes those fatty acids into basic essential energy.

PPAR Receptor Agonist

The salient feature of PPAR agonist is that their usage plays a dynamic role in the treatment of symptoms of metabolic syndrome specifically for triglycerides and blood sugar. These are the drugs which work on peroxiome proliferator-activated receptor. PPARs have the similarity with thyroid or steroid hormone and stimulation is caused in response to slight lipophilic ligands.

The involvement of PPAR is there in independent and DNA –dependent molecular and enzymatic pathways in adipose tissue, liver and skeletal muscles. The research is being conducted on wider level proving PPAR to be much effective in the treatment of certain diseases. PPAR (Proxisome Proliferate-Activated Receptors) have connection with ligand activated nuclear hormone receptors which have link with steroid receptor super family.


PPAR has great similarity with SARMs in working but there is only one difference. The difference is only of stimulating metabolism in the muscle tissues by targeting androgen receptors. This is why the glucose received by the muscles is instantly changed into energy instead of being stored in the muscles in the form of fats to be used further.

Cardarine Increases Good Cholesterol

Traditionally the medicines were formulated by different pharmaceutical companies to work out cholesterol related issues. Two types of cholesterol are found in human body; LDL cholesterol and HDL cholesterol. These cholesterol are responsible for many changes in the body both negative and positive. Quite contrary to LDL cholesterol that causes adverse health effects like heart attacks, strokes and artery blockage, HDL cholesterol apart from lessening LDL cholesterol with its harmful impacts, this cholesterol does bring healthy effects on the body.

Approximately for 30 years it has been used in the medicines. But for the last 20 years it has got drastically popular among athletes and bodybuilders. The product’s performance in changing the fat into energy was amazingly effective. This automatically reduced fats and enhanced strength and stamina to the required level making possible that was impossible.

Benefits of Cardarine

The purpose behind its formulation was to basically work on the reduction of bad cholesterol and giving a raise to good cholesterol. Apart from this preventing stomach from side effects was prioritized. The distinction of its working lies in its potency to strengthen muscles. Moreover, heart’s and brain’s function is enhanced. In reality Cardarine was formulated to resolve metabolic issues.

We are safe to say that Cardarine has drawn the attention of the bodybuilders in an amazing way for being so much effective in enhancement of performance duration. Cardarine too was originated to treat certain kinds of cancers and to do something effective to decrease the risks caused by the cholesterol. Plenty of benefits are associated with the usage of this drug.

Cardarine Improves Cardiovascular Performance

The hallmark of the compound is to boost up cardiovascular working. As the stamina is strengthened, the heart function gets improved with evoking a readiness in the user to perform more. The working gets improved as it has amazing effects on cardio session. The positive cardiac impacts get attached with the user during the cycle. As the of LDL cholesterol responsible for blocked arteries, is reduced with the use of cardarine, so the cardiovascular issues get recovered. Nitric oxide which has vasodilating properties is promoted with the use of Cardarine. Naturally, blood vessels are expanded for a better blood circulation

Cardarine Increases Stamina

Benefits of Cardarine

The most salient feature of Cardarine is that it boosts up metabolism that naturally strengthens stamina and improves endurance. It has amazingly positive impacts on fatigue.

Quick Fat Burning (Stack Cardarine with SR-9009)

If we say that Cardarine’s working is similar to that of SARMS, we are right. Interestingly, Cardarine works in a different way. As GW501516 while stacked with SR-9009 changes the glucose in energy to boost up metabolism instead of converting in fat to be used later, so very significant and promising results are there in connection with cutting the fats. Apart from this an enhanced performance strength and stamina is notably seen.

Positive Impact Of Cardarine on the Heart

Cardarine undoubtedly reduces the risks of heart attacks by working on blood flow regulation. The performance if heart is boosted up. Stamina to work more is improved. As it reduces LDL cholesterol which causes strokes, heart attacks and arteries blockage, so there is a promising progress in the function of heart. Even no weakness is reported during calorie loss period. So, stacking Cardarine with SR-9009 imparts full-body re-composition.

Muscle Growth

If we are taking Cardarine as the supplement to be used for bodybuilding purposes, then definitely we are making a very best choice.As it works very uniquely by changing glucose into energy instantly instead converting it into fat deposits, thus it gives a raise to muscle mass. This is the reason that bodybuilders very strongly recommend it for muscle mass. Moreover, it was originally formulated to work on the issue under discussion. So, we are safe to say that Cardarine is ideal for giving a raise to muscle mass.

Non Estrogenic

There is no doubt in it that the use of Cardarine brings about many health benefits we owe a great debt of gratitude of the product for ensuring safety on testosterone and estrogen levels. The most feared of problem related with the use of steroids are high blood pressure, gynecomastia, beefed up body, water retention and hair loss, but luckily Cardarine does not any of the mentioned adverse effects.

Wound Healing With Cardarine

If we are accepting Cardarine to be the best anti-inflammatory drug, then with no tinge of doubt, it can be considered very effective in wound healing. Moreover, it does not let the excessive amount of sugar to enter the blood, so this too play a very supportive role in wound healing process.

Post Cycle Therapy

This is as clear as crystal that Cardarine (GW-501516)is not a steroid. We all are well aware of the fact that PCT (Post Cycle Therapy) is conducted to avoid possibly related side effects which are typically associated with the use of anabolic steroids. So, no worries at all! Here we are secured to say that no PCT is needed.

Reduce Glucose Level

The excessive amount of glucose is converted into fat to be used later if a proper exercise is not done. Cardarine improves glucose consumption to cells, thus the level of glucose is reduced in the blood. This is how Cardarine is very effectively used to treat obesity and reducing the risks of type-2 diabetes mellitus.


So far benefits are concerned, we are safe to call it extremely effective in the treatment of certain diseases or resolving bodybuilding related issues. Though numerous health uses are there but it was specifically formulated to work out metabolic and heart related issues. Any one can use if one wants to go through wound healing process. Its results are promising in improved muscle growth.

It was specifically formulated to boost up metabolism, which supports very dynamically to heart health. As it very uniquely reduced bad cholesterol, thus gives an improvement to the working of heart.

Metabolism and Weight

Obesity or beefed up body is really a very big hindrance in the way to acquire well shaped toned body. Unfortunately bodybuilders despite strenuous exercise and observing a careful diet plan fail to shed the extra fats. This is because of poor metabolism. As a matter of fact Cardarine was originally formulated to boost metabolism rate.

The lipolysis is the mechanism that is activated during the process of remaining starved. Cardarine gives a raise to it. So, during starvation, the user doesn’t feel short of stamina and there is no muscle wasting. Cardarine is very well considered to be a treatment for obesity, as it converts deposits of fat into energy.

Metabolic Disorders

Here one well known maxim fits very well that is, “Excess o everything is bad.” Undoubtedly, glucose is considered to be playing a pivotal role in metabolic domain, but when amounts of glucose exceed the limits then hinder metabolism. Diabetes mellitus (DM) is a disorder of hyperglycemia.

In type-2 DM because of decreases insulin sensitivity, there is relative insulin scarcity. This thing does allow glucose to enter the cells. So, the use of Cardarine gives a raise to insulin sensitivity, thus reduces the risks of type-2 diabetes in a very effective way.

Role Of Cardarine in Sports

Role Of Cardarine in Sports

Amazingly, Cardarine has very dynamically got popular among the athletes because of its fat loss quality.As a matter of fact the drug was formulated by the pharmaceutical companies to work on metabolism, so Cardarine functions uniquely by instantly converting glucose received by the muscles into energy instead of depositing in the form o fats for further use.

This is how Cardarine strengthens stamina and improves endurance. These qualities are the most wanted by the bodybuilders and athletes. This is evident from the fact that WADA (World Anti Doping Agency) has banned GW501516 with other PPAR modulators on account of showing prominently improved performance. So, in this regard, International Drug committee conducts a urine test to detect the availability of the drug.

Cardarine Side Effects

Though Cardarine is considered to be highly side effect free drug but some potentially negative changes have been reported. Following adverse effects are reported to be found in the users:

Liver Damage

Studies conducted on mice have revealed that damaging liver is the most strongly associated negative impact of Cardarine. However, the process of research to know how damaging Cardarine is for human liver is still continued.

Significant Digestive Problems

Though the drug does not bring forth steroidal side effects but stomach related issues like diarrhea, constipation, stomach cramps, stomach aching and bowel troubles are reported to be found with the usage of Cardarine.

Can Cardarine Causes Cancer?

As a matter of no researches have proven the fact mentioned above. Studies are still ongoing. The fact revealed by the mice tests is that overdosing for a long period of time caused colon cancer. As excess of everything is bad, so 1000 times the recommended amount is definite to bring about adverse effects. Androgen do work both for causing and stopping cancer cells, so in depth and thorough clinical trials need to be conducted to draw definite statement supporting or condemning the motion.


The best suggested dosage is between 10-20mg, but the hasty user can increase the dose from 20 to get the desired results in an eye-wink to somehow. The recommended dose is 10mg but twice a day as its half –life comprises 16-24 hours. It will give a boost to its working.

Is it Legal?

Cardarine was banned by WADA (World Anti Doping Agency) because of its impacts on the performance of athletes. This is the reason the product’ sale is under red flag. However, the product is somehow fortunate as its sale is allowed to be used as a medicine or chemical to treat certain diseases as obesity and cholesterol related issues.

So, athletes need be well-aware of the side effects attached with the compound. Moreover, Australian government, due to one clinical study has also banned Cardarine recently. However, Something good can be expected.


Simply people find no way except going in the pursuit of some effectively amazing product which could perform a dual role of treating ailments and giving bodybuilding related benefits to the users. Naturally, people want to go for a safer solution for the purpose mentioned above. It is as clear as crystal that SARMS’s use does not come up with those adverse effects, as is caused by anabolic steroids. That’s why the compound magically drew the attention of the athletes.

Athletes strongly recommend its usage in enhancing performance duration and in giving a significant growth to muscle mass. Adaptability makes Cardarine popular among athletes. The product’s adverse effects on sport activities however, must not be ignored thoughtlessly. Demand of more and more research is still there in this regard. Cardarine not only gives a raise to muscle mass rather it reduces the fats as well by killing two birds with one stone. Moreover, it does not let body get affected with anabolic steroidal effects.


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